::: Welcome to Conservation Genome Resource Bank for Korean Wildlife :::
 
17_c.gif ¹®ÇåÁ¤º¸
17_c.gif ¾ß»ýµ¿¹°°ü·Ã ÀÚ·á ¹× ¼Ò½Ä
17_c.gif Á¾Á¤º¸
17_c.gif º¸ÀüÀ¯ÀüÇÐ/º¸Àü»ý¹°ÇÐ ÀÚ·á
17_c.gif ¾ß»ýµ¿¹°ÀÇÇÐ ¼Ò½Ä ¹× ÀÚ·á
  - õ¿¬±â³ä¹°ÀÇ ´ë»ó
sound.gif °¶·¯¸®
sound.gif ÀÚÀ¯°Ô½ÃÆÇ (¿¾³¯ °Ô½ÃÆÇ)
sound.gif °ü·Ã»çÀÌÆ®
sound.gif ÀÚ·á½Ç
sound.gif Ã£¾Æ¿À½Ã´Â ±æ
º¸ÀüÀ¯ÀüÇÐ/º¸Àü»ý¹°ÇÐ ÀÚ·á

View Article
Name
  ¿î¿µÀÚ 2005-11-28 23:14:47 | Hit : 24145 | Vote : 7588
Subject   [ÀÚ·á] Effects of mercury on neurochemical receptors in wild river otters (Lontra canadensis).
Environ Sci Technol. 2005 May 15;39(10):3585-91. Related Articles, Links  


Effects of mercury on neurochemical receptors in wild river otters (Lontra canadensis).

Basu N, Scheuhammer A, Grochowina N, Klenavic K, Evans D, O'Brien M, Chan HM.

Department of Natural Resource Sciences, Centerfor Indigenous Peoples' Nutrition and Environment (CINE), and School of Dietetics and Human Nutrition, McGill University, Saint Anne de Bellevue, Quebec, Canada H9X 3V9.

Fish-eating wildlife, such as river otters (Lontra canadensis), accumulate mercury (Hg) at concentrations known to impair animal behavior, but few studies have explored the underlying biochemical changes that precede clinical neurotoxicity. The objective of this study was to determine if Hg exposure can be related to concentrations of neurochemical receptors in river otters. River otter carcasses (n = 66) were collected in Ontario and Nova Scotia (Canada) by local trappers in 2002-2004. Concentrations of Hg (total and organic) were measured in the cerebral cortex and cerebellum. Saturation binding curves for the cholinergic muscarinic acetylcholine (mACh) receptor and dopamine-2 (D2) receptor were completed for each animal to calculate receptor density (Bmax) and ligand affinity (Kd). Negative correlations were found between concentrations of Hg and mACh receptor Bmax (r(total) Hg = -0.458, r(inorganic) Hg = -0.454, r(organic) Hg = -0.443) in the cerebral cortex. A negative correlation was also found between concentrations of total Hg and D2 receptor Bmax (r = -0.292) in the cerebral cortex. These results suggest that neurochemical receptors may prove useful as novel biomarkers of Hg exposure and neurotoxic effects in wildlife. Given the importance of cholinergic and dopaminergic systems in animal physiology, the ecological implications of these changes need to be investigated.

PMID: 15952362 [PubMed - indexed for MEDLINE]
 Prev   [ÀÚ·á] Eurasian otters, Lutra lutra, have a dominant mtDNA haplotype from the Iberian Peninsula to Scandinavia.
¿î¿µÀÚ
  2005/11/28 
 Next   [ÀÚ·á] The mitochondrial control region of Cervidae: evolutionary patterns and phylogenetic content.
¿î¿µÀÚ
  2005/11/21 


Copyright 1999-2024 Zeroboard / skin by daerew
151-742 ¼­¿ïƯº°½Ã °ü¾Ç±¸ ½Å¸²9µ¿ »ê56-1 ¼­¿ï´ëÇб³ ¼öÀÇ°ú´ëÇÐ 85µ¿ 802È£
Tel 02-888-2744, Fax 02-888-2754, E-mail cgrb@cgrb.org

Copyright © 2002-2004 CGRB All Rights Reserved