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  운영자 2006-05-29 11:21:17 | Hit : 12131 | Vote : 2804
Subject   [자료] 광견병 미끼예방약의 국내 야외적용
광견병 미끼예방약의 국내 야외적용

국립수의과학검역원1, 강원도가축위생시험소2, 경기도축산위생연구소3, 국립수목원4, 국립환경연구원5, 대한수의사회6, 국립수목원 국립환경연구원5, 대한수의사회6,

소병재1, 진영화1, 이상직4, 배유찬1, 손현주1, 정동수2, 이재구3, 박양순
2, 박성윤3, 이규현3, 원창만5, 강영배6

ABSTRACT

This study was conducted to establish the eradication plan by
using rabies bait vaccines in the Republic of Korea.
For the safety and efficacy of the oral rabies vaccine(Oral For the safety and efficacy of the oral rabies vaccine(Oral
SAG-1;Virbac,Raboral V-RG;Merial),five kinds of animals(raccoon
dogs,badgers,cats,dogs and mice)were tested.Neutralization
peroxidase linked assay(NPLA)was used in detecting neutralization
antibodies against rabies virus.Wild and domestic animals which were antibodies against rabies virus.Wild and domestic animals which were orally administered one and two or ten doses had no adverse events
due to vaccine and specific pathological lesions,respectively.Viral
Neutralization antibodies(VNA)in raccoon dogs were first detected 2
weeks post-ingestion(oral administration).VNA could be detected 4
weeks post-ingestion(oral administration)in all raccoon dogs.weeks post-ingestion(oral administration)in all raccoon dogs.
We tried the field trial of oral rabies vaccine(Raboral
V-RG;Merial)on five cities in Kyonggi and Kangwon Provinces,i.e.,
Paju city,Dhongducheon city,Youncheon-gun,Cholwon-gun,
Hwacheon-gun,among rabies infected regions.Seventy-five percentage
of the vaccine were ingested in case of Cholwon-gun region 30 days
after applying bait vaccine.Average antibody forming rate in raccoon
dogs captured in the applied five cities was 32%(10/31)during April dogs captured in the applied five cities was 32%(10/31)during April
to November 2001.Neutralizing antibodies against rabies virus could
not be detected in raccoon dogs and cats captured in other regions
during the same period.Also,Rabies cases in the applied area were
decreased or were not reported during 4 5 months after applying ~decreased or were not reported during 4 5 months after applying ~
rabies bait vaccine.
Key words:rabies,bait vaccine,raccoon dogs,safety,efficacy,
field trial field trial


http://211.241.91.20/Oat/data/2003/full_text/pdf/O200300022.pdf
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운영자
  2006/06/07 
 Next   [자료] Rabies, an Emerging Disease in Korea
운영자
  2006/05/29 


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