::: Welcome to Conservation Genome Resource Bank for Korean Wildlife :::
 
17_c.gif 문헌정보
17_c.gif 야생동물관련 자료 및 소식
17_c.gif 종정보
17_c.gif 보전유전학/보전생물학 자료
17_c.gif 야생동물의학 소식 및 자료
  - 천연기념물의 대상
sound.gif 갤러리
sound.gif 자유게시판 (옛날 게시판)
sound.gif 관련사이트
sound.gif 자료실
sound.gif 찾아오시는 길
야생동물의학 소식 및 자료

View Article
Name
  운영자 2006-07-18 19:17:45 | Hit : 12374 | Vote : 4173
Subject   [자료] Airborne transmission of lyssaviruses.
J Med Microbiol. 2006 Jun;55(Pt 6):785-90. Related Articles, Links  


Airborne transmission of lyssaviruses.

Johnson N, Phillpotts R, Fooks AR.

Rabies and Wildlife Zoonoses Group, Veterinary Laboratories Agency (VLA, Weybridge), WHO Collaborating Centre for the Characterisation of Rabies and Rabies-related Viruses, New Haw, Addlestone KT15 3NB, UK.

In 2002, a Scottish bat conservationist developed a rabies-like disease and subsequently died. This was caused by infection with European bat lyssavirus 2 (EBLV-2), a virus closely related to Rabies virus (RABV). The source of this infection and the means of transmission have not yet been confirmed. In this study, the hypothesis that lyssaviruses, particularly RABV and the bat variant EBLV-2, might be transmitted via the airborne route was tested. Mice were challenged via direct introduction of lyssavirus into the nasal passages. Two hours after intranasal challenge with a mouse-adapted strain of RABV (Challenge Virus Standard), viral RNA was detectable in the tongue, lungs and stomach. All of the mice challenged by direct intranasal inoculation developed disease signs by 7 days post-infection. Two out of five mice challenged by direct intranasal inoculation of EBLV-2 developed disease between 16 and 19 days post-infection. In addition, a simple apparatus was evaluated in which mice could be exposed experimentally to infectious doses of lyssavirus from an aerosol. Using this approach, mice challenged with RABV, but not those challenged with EBLV-2, were highly susceptible to infection by inhalation. These data support the hypothesis that lyssaviruses, and RABV in particular, can be spread by airborne transmission in a dose-dependent manner. This could present a particular hazard to personnel exposed to aerosols of infectious RABV following accidental release in a laboratory environment.

PMID: 16687600 [PubMed - indexed for MEDLINE]


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=16687600&query_hl=1&itool=pubmed_docsum
 Prev   [자료] Natural and experimental West Nile virus infection in five raptor species.
운영자
  2006/07/18 
 Next   [소식] FAO warns against killing wild birds to fight bird flu
운영자
  2006/07/10 


Copyright 1999-2021 Zeroboard / skin by daerew
151-742 서울특별시 관악구 신림9동 산56-1 서울대학교 수의과대학 85동 802호
Tel 02-888-2744, Fax 02-888-2754, E-mail cgrb@cgrb.org

Copyright © 2002-2004 CGRB All Rights Reserved