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  운영자 2007-02-05 21:38:22 | Hit : 8983 | Vote : 2449
Subject   [자료] Rabies and other lyssavirus diseases
Rabies and other lyssavirus diseases

M J Warrell, D A Warrell


Lancet 2004; 363: 959–69

Nuffield Department of Clinical Medicine, John Radcliffe Hospital,
Oxford OX3 9DU, UK (M J Warrell FRCPath, Prof D A Warrell FMedSci)
(e-mail: mary.warrell@ndm.ox.ac.uk)

The full scale of the global burden of human rabies is unknown, owing to inadequate surveillance of this fatal disease. However, the terror of hydrophobia, a cardinal symptom of rabies encephalitis, is suffered by tens of thousands of people each year. The recent discovery of enzootic European bat lyssavirus infection in the UK is indicative of our
expanding awareness of the Lyssavirus genus. The main mammalian vector species vary geographically, so the health problems created by the lyssaviruses and their management differ throughout the world. The methods by which these neurotropic viruses hijack neurophysiological mechanisms while evading immune surveillance is beginning to be unravelled by, for example, studies of molecular motor transport systems. Meanwhile, enormous challenges remain in
the control of animal rabies and the provision of accessible, appropriate human prophylaxis worldwide.

 Prev   [자료] Unifying the spatial population dynamics and molecular evolution of epidemic rabies virus
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