::: Welcome to Conservation Genome Resource Bank for Korean Wildlife :::
 
17_c.gif 문헌정보
17_c.gif 야생동물관련 자료 및 소식
17_c.gif 종정보
17_c.gif 보전유전학/보전생물학 자료
17_c.gif 야생동물의학 소식 및 자료
  - 천연기념물의 대상
sound.gif 갤러리
sound.gif 자유게시판 (옛날 게시판)
sound.gif 관련사이트
sound.gif 자료실
sound.gif 찾아오시는 길
야생동물의학 소식 및 자료

View Article
Name
  운영자 2007-02-26 17:03:34 | Hit : 9156 | Vote : 2452
Subject   [자료] The evolution of epidemic influenza
Review

Nature Reviews Genetics 8, 196-205 (March 2007)doi:10.1038/nrg2053

The evolution of epidemic influenza

Martha I. Nelson1 and Edward C. Holmes1,2

Abstract

Recent developments in complete-genome sequencing, antigenic mapping and epidemiological modelling are greatly improving our knowledge of the evolution of human influenza virus at the epidemiological scale. In particular, recent studies have revealed a more complex relationship between antigenic evolution, natural selection and reassortment than previously realized. Despite these advances, there is much that remains to be understood about the epidemiology of influenza virus, particularly the processes that determine the virus's strong seasonality. We argue that a complete understanding of the evolutionary biology of this important human pathogen will require a genomic view of genetic diversity, including the acquisition of polymorphism data from within individual hosts and from geographical regions, particularly the tropics, which have been poorly surveyed to date.

affiliations

1. Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
2. Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA.

Correspondence to: Edward C. Holmes1,2 Email: ech15@psu.edu


http://www.nature.com/nrg/journal/v8/n3/abs/nrg2053.html
 Prev   [자료] Single-dose intravenous and oral pharmacokinetics of enrofloxacin in goral (Nemorrhaedus goral arnouxianus)
운영자
  2007/03/05 
 Next   [자료] Wildlife Veterinarian, Conservation and Public Health
운영자
  2007/02/19 


Copyright 1999-2020 Zeroboard / skin by daerew
151-742 서울특별시 관악구 신림9동 산56-1 서울대학교 수의과대학 85동 802호
Tel 02-888-2744, Fax 02-888-2754, E-mail cgrb@cgrb.org

Copyright © 2002-2004 CGRB All Rights Reserved