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2006-05-29 11:21:17 | Hit : 23181 | Vote : 8595 |
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[ÀÚ·á] ±¤°ßº´ ¹Ì³¢¿¹¹æ¾àÀÇ ±¹³» ¾ß¿ÜÀû¿ë |
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±¤°ßº´ ¹Ì³¢¿¹¹æ¾àÀÇ ±¹³» ¾ß¿ÜÀû¿ë
±¹¸³¼öÀÇ°úÇа˿ª¿ø1, °¿øµµ°¡ÃàÀ§»ý½ÃÇè¼Ò2, °æ±âµµÃà»êÀ§»ý¿¬±¸¼Ò3, ±¹¸³¼ö¸ñ¿ø4, ±¹¸³È¯°æ¿¬±¸¿ø5, ´ëÇѼöÀÇ»çȸ6, ±¹¸³¼ö¸ñ¿ø ±¹¸³È¯°æ¿¬±¸¿ø5, ´ëÇѼöÀÇ»çȸ6,
¼Òº´Àç1, Áø¿µÈ1, ÀÌ»óÁ÷4, ¹èÀ¯Âù1, ¼ÕÇöÁÖ1, Á¤µ¿¼ö2, ÀÌÀ籸3, ¹Ú¾ç¼ø
2, ¹Ú¼ºÀ±3, À̱ÔÇö3, ¿ø⸸5, °¿µ¹è6
ABSTRACT
This study was conducted to establish the eradication plan by
using rabies bait vaccines in the Republic of Korea.
For the safety and efficacy of the oral rabies vaccine(Oral For the safety and efficacy of the oral rabies vaccine(Oral
SAG-1;Virbac,Raboral V-RG;Merial),five kinds of animals(raccoon
dogs,badgers,cats,dogs and mice)were tested.Neutralization
peroxidase linked assay(NPLA)was used in detecting neutralization
antibodies against rabies virus.Wild and domestic animals which were antibodies against rabies virus.Wild and domestic animals which were orally administered one and two or ten doses had no adverse events
due to vaccine and specific pathological lesions,respectively.Viral
Neutralization antibodies(VNA)in raccoon dogs were first detected 2
weeks post-ingestion(oral administration).VNA could be detected 4
weeks post-ingestion(oral administration)in all raccoon dogs.weeks post-ingestion(oral administration)in all raccoon dogs.
We tried the field trial of oral rabies vaccine(Raboral
V-RG;Merial)on five cities in Kyonggi and Kangwon Provinces,i.e.,
Paju city,Dhongducheon city,Youncheon-gun,Cholwon-gun,
Hwacheon-gun,among rabies infected regions.Seventy-five percentage
of the vaccine were ingested in case of Cholwon-gun region 30 days
after applying bait vaccine.Average antibody forming rate in raccoon
dogs captured in the applied five cities was 32%(10/31)during April dogs captured in the applied five cities was 32%(10/31)during April
to November 2001.Neutralizing antibodies against rabies virus could
not be detected in raccoon dogs and cats captured in other regions
during the same period.Also,Rabies cases in the applied area were
decreased or were not reported during 4 5 months after applying ¢¦decreased or were not reported during 4 5 months after applying ¢¦
rabies bait vaccine.
Key words:rabies,bait vaccine,raccoon dogs,safety,efficacy,
field trial field trial
http://211.241.91.20/Oat/data/2003/full_text/pdf/O200300022.pdf |
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